diff --git a/__tests__/version/requirements-file.test.ts b/__tests__/version/requirements-file.test.ts
index 5ff0277..11f9ebf 100644
--- a/__tests__/version/requirements-file.test.ts
+++ b/__tests__/version/requirements-file.test.ts
@@ -35,3 +35,14 @@ test("strips PEP 508 markers from requirements dependencies", () => {
 
   expect(parsedVersion).toBe("==0.11.20");
 });
+
+test.each([
+  ["uv >= 0.5.0", ">=0.5.0"],
+  ["uv == 0.11.20", "==0.11.20"],
+  ["uv>=0.5.0, <0.6.0", ">=0.5.0,<0.6.0"],
+  ["uv >= 0.5.0 , < 0.6.0", ">=0.5.0,<0.6.0"],
+  ["uv==0.11.20 --hash=sha256:abc", "==0.11.20"],
+  ["uv==0.11.20  # pinned for CI", "==0.11.20"],
+])("allows whitespace in the uv specifier %s", (dependency, expected) => {
+  expect(getUvVersionFromRequirementsText(dependency)).toBe(expected);
+});
diff --git a/dist/setup/index.cjs b/dist/setup/index.cjs
index 0b7cf0c..0390261 100644
--- a/dist/setup/index.cjs
+++ b/dist/setup/index.cjs
@@ -101579,7 +101579,7 @@ function getUvVersionFromAllDependencies(allDependencies) {
 }
 function getUvVersionFromDependency(dependency) {
   const dependencyWithoutMarker = dependency.split(";", 1)[0]?.trim();
-  return dependencyWithoutMarker?.match(/^uv([=<>~!]+\S*)/)?.[1].trim();
+  return dependencyWithoutMarker?.match(/^uv\s*((?:[=<>~!]+\s*[^\s,]+\s*,?\s*)+)/)?.[1].replace(/\s/g, "");
 }
 
 // src/version/tool-versions-file.ts
diff --git a/src/version/requirements-file.ts b/src/version/requirements-file.ts
index 401a2c1..e335c5f 100644
--- a/src/version/requirements-file.ts
+++ b/src/version/requirements-file.ts
@@ -69,5 +69,7 @@ function getUvVersionFromAllDependencies(
 
 function getUvVersionFromDependency(dependency: string): string | undefined {
   const dependencyWithoutMarker = dependency.split(";", 1)[0]?.trim();
-  return dependencyWithoutMarker?.match(/^uv([=<>~!]+\S*)/)?.[1].trim();
+  return dependencyWithoutMarker
+    ?.match(/^uv\s*((?:[=<>~!]+\s*[^\s,]+\s*,?\s*)+)/)?.[1]
+    .replace(/\s/g, "");
 }